AAGP® could prove useful in anti-aging skincare and cosmetics

Environmental exposures such as sun and wind can affect how our skin ages, reducing elasticity, decreasing suppleness and causing wrinkles.

AAGP®’s strong cell preservation properties could help extend the life of skin cells, reducing the signs of aging. In a global market that’s already nearing $400 billion in value, AAGP®’s potential application in creating the best anti-aging skincare in the cosmetics industry is cause for excitement.

Causes of Aging Skin

Time spent outdoors contributes to increased UV exposure, which in turn speeds up the body’s natural aging process, which is already in effect in everyone. Cells under increased UV exposure are susceptible to inflammation and even cell death.

In addition to UV exposure and the body’s natural aging process, water exposure can serve to dry out skin and hasten the loss of elasticity, resulting in wrinkle formation as well.

The signs of aging

The signs of aging are commonly seen in the appearance of wrinkles and spots, which form due to a few important factors:

  • Ultraviolet (UV) radiation in the form of sun exposure
  • Repeated Water exposure
  • Age

AAGP® as a solution

What makes AAGP® so exciting is the potential it holds for healing, protecting and even preventing cell damage due to inflammation and UV exposure.

In the discovery phase of our research, we saw how AAGP®’s cell preservation properties protected skin fibroblasts that were exposed to oxidative stress, such as what causes the signs of aging. This protective quality persisted not only when hours of exposure were increased, but also when the concentration of AAGP® for test cells was decreased.

A product with the ability to reduce inflammation and heal skin cells from UV radiation would be valuable indeed, and ProtoKinetix is leading the way. Our research into creating the best anti-aging skincare is only just beginning.

ProtoKinetix research and clinical trials

Find out what we’ve learned so far about the impact AAGP® could have in the anti-aging skincare and cosmetics industry.

Market potential for cosmetics and anti-aging skincare

There is huge demand for effective anti-aging products. In 2019, the cosmetics industry as a whole was valued at $380 billion. It’s expected to be worth $463.5 billion by 2027 at a CAGR of 5.3%, according to one study¹.

An increasingly aging population in developed markets is one driver of this growth, while increased consumer demand coupled with increased consumer awareness is shaping the types of skincare products desired. The anti-aging cosmetics market as a slice of this sector was valued at $38.6 billion in 2018 and projected to nearly double by 2026, forecasted at $60.3 billion. It is clear that there is a market for anti-aging cosmetics that are safe and effective, and ProtoKinetix is researching ways to create anti-aging skincare products that really work.

¹PR Newswire

2019 Market Revenue:

$380.2 Billion

2027 Market Forecast:

$463.5 Billion

Applications of AAGP® in Dermatology

Lip Balm mobile

Lip Balm

The sun’s rays don’t damage only skin — they can cause damage and inflammation for lips, too. AAGP® may hold the key to treating sunburned lips thanks to its unique ability to protect cells against inflammation. Join us as we explore the potential of a lip balm or treatment containing AAGP®.

Dermatological Inflammation

Millions of people suffer with inflamed, uncomfortable skin. In fact, more than 1 in 4 Americans (26%) have at least one skin disease, according to the American Academy of Dermatology.

Inflammatory skin conditions are the most common dermatological issue, but researchers are exploring how AAGP© can help.

Research Pipeline for Dermatology:

Inflammation protection


The most common dermatological issue is inflammation. This can cause chronic conditions like eczema or rosacea. Occasional rashes can also occur from exposures to natural or chemical agents and sensitivities.

Your skin is your largest organ. When it becomes inflamed, visible reactions can happen. Figuring out what’s wrong and getting your skin back to normal is hard enough without answering questions from family and strangers about what’s wrong with your skin.

We’re in the preclinical research stage of discovering AAGP®’s ability to protect skin from inflammation and are working hard to advance AAGP® to clinical skin trials.

UV radiation and burn recovery


Currently, we’re in the discovery phase to understand how AAGP® can help skin recover from UV radiation and burns. Ultraviolet light can damage proteins and DNA in skin cells. It can also produce inflammatory mediators that increase cell death or alter skin elasticity and color.

In our research, we’ve learned that AAGP® could protect human adult skin fibroblasts against high intensity UVA and UVC wavelengths, which suggest that AAGP mechanisms of cell protection could both protect and renew healthy skin. We’ll soon be moving on to the proof of concept and into preclinical stages of research.

Explore other Industry applications for AAGP®


Support our research into anti-aging skincare, cosmetics and treatments while also supporting your financial future. Contact your broker, or reach out to our team at ProtoKinetix to learn about potential investment options.

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