Diabetic Retinopathy

ProtoKinetix could hold the key to protecting and healing retinas

In addition to other complications, diabetes can adversely affect the eyes by causing diabetic retinopathy, or damage and deterioration of the blood vessels in the retina. In fact, diabetic retinopathy is the number one cause of blindness in young adults, according to the American Academy of Family Physicians. And 1 in 3 diabetics over 40 will experience retinopathy to some degree. This could be as many as 120 million people, though many more are undiagnosed. Sadly, more than 800,000 people have gone blind due to diabetic retinopathy.

AAGP® could play an important part in addressing the devastating side effects of this disease and healing the eye from diabetic retinopathy, thanks to its protective potential to heal the cells of the retina.


Diabetic retinopathy causes

According to the American Academy of Ophthalmology, the high blood sugar caused by diabetes can harm the small blood vessels of the eye, causing blockages specifically affecting the retina. Sometimes, the body tries to build new blood vessels, but these, too, are weak or damaged by the hostile effects of diabetes. The result is blurry vision and sometimes even blindness.

There are two stages of diabetic retinopathy: early, Non-Proliferative Diabetic Retinopathy (NPDR), and the serious and more advanced stage, called Proliferative Diabetic Retinopathy (PDR).

During the early stage, small leaks in the blood vessels can cause swelling (macular edema) and blockages (macular ischemia). As the disease progresses to the advanced stage, blood may leak from malformed blood vessels into the vitreous material of the eye, sometimes causing scar tissue, dark spots in vision, or even a detached retina.

Diabetic retinopathy symptoms

In the early stages of diabetic retinopathy, the patient may not notice many changes in vision. Left undiagnosed and untreated, it can lead to blindness. Symptoms of diabetic retinopathy include:

  • Dark, floating spots in your vision
  • Blurry vision, including vision that goes from blurry to clear
  • Poor night vision
  • Loss of vision
  • Impairment of your ability to see color

According to the Mayo Clinic, diabetic retinopathy will usually affect both of the patient’s eyes.

Microscope image

Treatments for diabetic retinopathy

There is no cure for diabetes, only management. For people with diabetes, careful monitoring of vision is important, and should include regular eye exams with dilation. Disciplined regulation of blood sugar and blood pressure is also critically important to prevent severe vision loss. Preventative medicine strategies could also be an option if they can be developed to protect the small blood vessels and cells of the retina.

There are some laser treatments and surgeries that show benefits to addressing the blood vessels of the retina, but the lack of affordability of these treatments leaves an opening for other innovations to grab market share.

AAGP® as a potential solution

But just because there is no cure yet for diabetes yet does not mean that people must resign themselves to deteriorating vision. At ProtoKinetix, we believe AAGP® holds an important key to defending against vision loss and the potential to improve quality of life to people suffering from diabetic retinopathy. That’s because our proprietary glycopeptide holds the promise of aiding the blood vessels and cells of the retina, which could stop or even reverse the leaks and blockages of this disease if a path forward is established in the normal care strategy.

ProtoKinetix research and clinical trials

See the promising results our research has yielded so far, which indicates the ways AAGP® could be used to enable regeneration of retinal cells. You can review our research pipeline to see the status of our active research as we strive toward answers.

Market potential for diabetic retinopathy

While we are greatly encouraged by the results of our research so far, we require the support of investors like you to bring treatments to market. The market for diabetic retinopathy is projected to see 6.9% CAGR to 2025, from an $8 billion valuation in 2018 to a projected $12 billion in 2025.

2018 Market Revenue:

$8 Billion

2025 Market Forecast:

$12 Billion


Support our research into healing diabetic retinopathy while supporting your financial future. Contact your broker or reach out to our team at ProtoKinetix to learn about potential investment options.

  • This field is for validation purposes and should be left unchanged.