Dry Eye Disease

How AAGP® could help break through current treatment barriers

According to the Mayo Clinic, dry eye disease occurs when our bodies cannot produce enough tears to adequately lubricate our eyes. This can result in discomfort, itching, stinging, burning and even vision problems. 

Based on a 2017 report on the prevalence of dry eye disease, this common condition affects approximately 6.8% of the US adult population (or 16.4 million people). Women are nearly twice as affected as men, and prevalence tends to increase with age.


The causes of dry eye disease

There is no single cause for dry eye disease. Any inflammation of the tear glands or tear ducts could lead to impaired tear production and discomfort. Common factors that may result in dry eye disease include stress from air pollution, genetics, the effects of aging and damage caused by chronic conditions, such as Type 1 diabetes, arthritis and menopause.

The symptoms of dry eye disease

While the causes of dry eye disease are diverse, the symptoms are generally the same. Often, individuals suffering from dry eye disease may experience:

  • Blurry vision
  • Difficulty driving at night
  • Discomfort while wearing contacts
  • Irritation and redness
  • Itching, stinging, burning or soreness
  • Light sensitivity
  • Mucus in or around the eye
Microscope image

Treatments for dry eye disease

Current dry eye disease treatments target the symptoms of dry eye disease – the dryness and discomfort – by replicating the effects of tears and replacing moisture in the eyes. Unfortunately, this is a temporary solution, and those who use tear replacement methods typically need to do so indefinitely. Over time, heavy eye drop use may even exacerbate the symptoms of dry eye disease.

AAGP® as a potential solution

With AAGP®, our proprietary anti-aging glycopeptide , ProtoKinetix researchers are investigating ways in which cell preservation can be utilized to help with tear production, addressing the causes of dry disease. We are in the process of formulating our own prescription and over-the counter eye drops that would not only provide temporary moisture to the eye but also help target and reverse cell damage in the tear ducts and glands.

ProtoKinetix research and clinical trials

Initial formulations of these ProtoKinetix eye drops are complete, and pre-clinical trials are underway with plans for a phase-1 trials soon, with extremely promising results thus far. Read our recent press releases to see where our research is at today and what’s coming next:

Market potential for dry eye disease

While our research progress has been extremely positive, we need the support of dedicated investors to get our eye drop solution to market. According to research from Market Scope, global revenues for dry eye treatments are expected to increase from $4.6 billion in 2018 to $6.2 billion in 2023, due in part to the increasing elderly population and awareness of dry eye disease treatments. The opportunity is immense, and we hope you’ll join us on this exciting journey.

2018 Market Revenuet:

$4.6 Billion

2023 Market Forecast:

$6.2 Billion


Support our dry eye disease research while you support your financial future. Contact your broker or reach out to the team at ProtoKinetix to learn about potential investment options.

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